Research into a cure
The goal of the Histiocytosis Association's Research Program is to establish better treatments and a cure for those affected with histiocytosis, ultimately effecting the prevention of such diseases. To date, the Histiocytosis Association of America has funded over 80 research projects.
The objectives of the Research Program are:
- To fund worthy scientific research projects.
- To educate physicians and scientists.
- To encourage and support symposia into histiocytic disorders.
- To directly participate in research projects.
- To encourage publication of scientific information.
In 2007 funds raised by Hike For A Cure supported the following research projects:
- Lymphocyte Trafficking in Langerhans Cell Histiocytosis.
Principal Investigators: Carl Allen, MD, PhD and Kenneth McClain, MD, PhD, Texas Children’s Cancer Center/Hematology Service - Houston, Texas USA.
Awarded: December 2007
- Investigations into the Clinical and Molecular Mathogenesis of XIAP Deficiency.
Principal Investigators: Rebecca Marsh MD; Jack J. H. Bleesing MD, PhD; Kimberly Risma MD, PhD; Lisa Filipovich MD Cincinnati Children's Hospital – Cincinnati, Ohio USA.
Awarded: December 2007
- A Transgenic Mouse Model Mimicking Abnormal Langerhans Cell Trafficking in Langerhans Cell Histiocytosis.
Principal Investigators: Barbara Brandner, PhD and Barrett J. Rollins, MD, PhD Dana-Farber Cancer Institute, Harvard Medical School.
Awarded: December 2007
- Role of the Granzyme Inhibitor Proteinase Inhibitor-9 (PI-9) in Langerhans Cell Histiocytosis.
Principal Investigator: Carl Friedrich Classen, MD University Childrens Hospital Rostock - Duisburg, Germany.
Awarded: December 2007
- Completion of data collection and analysis for the LCH III international treatment protocol. Findings from this study have are already being factored in to patient treatment protocols around the world.
To learn more about research into histiocytosis, click on the following links:
